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Epistasis. Interestingly, the word “epistasis” is composed of Greek roots that mean “standing upon.” A good example of epistasis is coat color in the popular dog breed the Labrador retriever. Labrador retriever coat color genes。

Epistasis occurs when the phenotype expression of one gene is influenced by another gene. Example: Gene A must be present for Gene B to express a certain trait. Example: The coat color in mice is a classic example。

Epistasis is fundamental to the structure and function of genetic pathways and to the evolutionary dynepitasiamics of complex genetic systems. High-throughput functional genomics, systems-level ...

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